DIREQT2Heart

📍 CCMAR - Portugal

About DIREQT2Heart

A DIRect QuanTitative assessment of Heart disease with magnetic resonance imaging. It is a project that Prompt diagnosis of coronary heart disease to prevent early mortality. The consortium is led by Teresa Matias Correia from CCMAR and includes Rita Nunes from Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento (ISR), Carlos Alberola-López from University of Valladolid and Borja Ibáñez from Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC).

Coronary heart disease

Coronary heart disease (CHD), which is the leading cause of death worldwide, occurs when blood flow to the heart becomes restricted. Early detection of this condition is of paramount importance for preventing life-threatening events.

Cardiac MRI 🧲

Our research is also focused on the development of accelerated acquisition, undersampled reconstruction and motion correction techniques for free-breathing cardiac Magnetic Resonance Imaging (MRI) for diagnosing cardiovascular disease. We are particularly interested in the application of these methods to 3D whole-heart cardiac MRI and quantitative first-pass myocardial perfusion and their translation into clinical practice.

Deep Learning 👩🏻‍💻

Our active research projects aim to develop deep learning-based methods for image reconstruction from accelerated scans, automated detection, segmentation and classification tasks for diagnosis, prognosis, and therapy response prediction.

Sep 202329

Prevención, diagnóstico y tratamiento: la ciencia se vuelca en el cuidado del corazón

Apr 202317

¿Cómo mejorar la detección precoz de las enfermedades coronarias?

Jan 202324

A ciência à descoberta do coração

Dec 202211

Melhores imagens para melhores diagnósticos

Dec 20225

E se a ressonância magnética pudesse fazer imagens melhores?

Sep 20221

Iberian Consortium Awarded a “la Caixa” Foundation Health Research Grant

People 📰

Teresa Matias Correia (Project Leader) CCMAR

Rita Nunes - IST-ID

Carlos Alberola-López - University of Valladolid

Borja Ibáñez - CNIC

👉 Full team

Publications 📰

Journal publications and conference proceedings

👉 Full list

A Gaspar, NA Silva, AM Ferreira, RG Nunes. Repeatability of Open-MOLLI: An open-source inversion recovery myocardial T1 mapping sequence for fast prototyping. Magn Reson Med. 2024; 92: 741-750. https://doi.org/10.1002/mrm.30080.

A Binek, C Castans, I Jorge, N Bagwan, JM Rodríguez, R Fernández-Jiménez, C Galán-Arriola, E Oliver, M Gómez, A Clemente-Moragón, et al. Oxidative Post-translational Protein Modifications upon Ischemia/Reperfusion Injury. Antioxidants. 2024; 13(1):106. https://doi.org/10.3390/antiox13010106.

T Correia. Inteligência artificial na ressonância magnética cardíaca – o impulso que faltava? LIFESAVING Magazine #29 https://doi.org/10.5281/zenodo.10418257.

M Obando, A Bassi, N Ducros, G Mato, Teresa M. Correia. ToMoDL: A model-based deep learning framework for optical projection tomography. https://doi.org/10.21203/rs.3.rs-3318045/v1.

M Obando, A Bassi, N Ducros, G Mato, Teresa M. Correia. Model-based deep learning framework for accelerated optical projection tomography. Sci Rep 13, 21735 (2023). https://doi.org/10.1038/s41598-023-47650-3.

Olausson T, et al. Time-Resolved Cardiac function: Myocardium Strain and First-Pass Perfusion Using MR-MOTUS. 32nd International Society for Magnetic Resonance in Medicine (ISMRM), 4-9 May, Singapore, Abstract 0629 (2024)

Santinha J, Correia T. Radiomics Predictive Model of Myocardial Infarction and Microvascular Obstruction. 4th ISMRM Iberian Chapter Annual Meeting, 2-3 July, Porto, Portugal, P61 (2024)

Santos J, et al. Development of a deep-learning tool for automatic Cardiac CMR planning. 4th ISMRM Iberian Chapter Annual Meeting, 2-3 July, Porto, Portugal, P59 (2024)

Amil M, et al. Accelerating Cardiac Magnetic Resonance T1-Mapping using an Efficient Deep Learning Reconstruction. 4th ISMRM Iberian Chapter Annual Meeting, 2-3 July, Porto, Portugal, P55 (2024)

Gaspar A, et al. T1 mapping with radial Open-MOLLI. 4th ISMRM Iberian Chapter Annual Meeting, 2-3 July, Porto, Portugal, P40 (2024)

Carvalho C, et al. Accelerated MRI Parametric Mapping with PENGUIN. 4th ISMRM Iberian Chapter Annual Meeting, 2-3 July, Porto, Portugal, O1 (2024)

Moya-Sáez E, et al. A comparative analysis of different respiratory motion correction approaches in free-breathing first-pass perfusion cardiac MR. 4th ISMRM Iberian Chapter Annual Meeting, 2-3 July, Porto, Portugal, P48 (2024)

Villacorta-Aylagas P, et al. A KomaMRI Phantom Extension for Integrated Dynamic Imaging. 32nd International Society for Magnetic Resonance in Medicine (ISMRM), 4-9 May, Singapore, Abstract 4684 (2024)

Santinha J, Correia T. RAMI: Radiomics Predictive Model of Myocardial Infarction and Microvascular Obstruction. 32nd International Society for Magnetic Resonance in Medicine (ISMRM), 4-9 May, Singapore, Abstract 3386 (2024)

Gaspar A, et al. Test-retest of open-source inversion recovery myocardial T1 mapping sequence (Open-MOLLI) for fast prototyping. 19th European Molecular Imaging Meeting (EMIM), 12-15 March, Porto, Portugal, Abstract TECH-052 (2024)

Moya-Sáez E, et al.Post-contrast multi-parametric mapping from only pre-contrast conventional weighted images. 32nd International Society for Magnetic Resonance in Medicine (ISMRM), 4-9 May, Singapore, Abstract 2809 (2024)

Carvalho C, et al. Integrating Quantitative Mapping into Physics-Based Deep Learning for Improved Accelerated Image Reconstruction. 32nd International Society for Magnetic Resonance in Medicine (ISMRM), 4-9 May, Singapore, Abstract 4505 (2024)

M Ángel Martín-Fernández, P Irarrazaval, C Castillo-Passi, C Alberola-López. Optimal isochromat frequencies for T2* spin-level simulation. ESMRMB annual meeting P229 (2023).

M Ángel Martín-Fernández, P Irarrazaval, C Castillo-Passi, C Alberola-López. Efficient T2* spin-level simulation. 3rd ISMRM Iberian Chapter meeting,P2.9 (2023).

J Rodríguez-Galván, S Merino-Caviedes, D Filgueiras-Rama, J Sánchez-González, A Tristán-Vega, C Alberola-López. Beyond DTI: Higher order models in Cardiac dMRI. 3rd ISMRM Iberian Chapter meeting, P1.16 (2023).

J Rodríguez-Galván, S Merino-Caviedes, D Filgueiras-Rama, J Sánchez-González, A Tristán-Vega, C Alberola-López. Applying diffusion signal representation further than DTI improves cardiac dMRI insights. 31th ISMRM meeting (2023).

A Gaspar, N ASilva, A Ferreira, R Nunes. Repeatability of Open-source inversion recovery myocardial T1 mapping sequence (Open-MOLLI) for fast prototyping.3rd ISMRM Iberian Chapter meeting (2023).

C Carvalho, R Nunes, T Correia. Diving into Extended Phase Graph-based Deep Learning for Accurate and Fast T2 Mapping with PENGUIN. 3rd ISMRM Iberian Chapter meeting (2023). https://doi.org/10.5281/zenodo.10413035.

A Gaspar, N ASilva, A Ferreira, R Nunes. Repeatability of ProMyoT1: an open-source inversion recovery myocardial T1 mapping sequence for fast prototyping. 31th ISMRM meeting. (2023). PDF

T Correia. MR Techniques for Quantifying Myocardial Perfusion. 31th ISMRM meeting, 4505. (2023). https://doi.org/10.5281/zenodo.10418111

C Carvalho, R Nunes, T Correia. Diving into Extended Phase Graph-based Deep Learning for accurate T2 mapping with PENGUIN. 31th ISMRM meeting, 1090 (2023). https://doi.org/10.5281/zenodo.10413082

P Osório, M Henningsson, H Alberto Gomez, R Nunes, T Correia. DeepCardioPlanner: Deep Learning-based tool for automatic CMR planning. 31th ISMRM meeting, 5134 (2023). https://doi.org/10.5281/zenodo.10419711

E Martín-González, E Alskaf, A Chiribiri, P Casaseca-de-la-Higuera, C Alberola-López, R Nunes, T Correia. The deep SECRET to accelerated first-pass perfusion cardiac MRI. 30th ISMRM meeting, 299 (2022).

T Correia. Cardiac Perfusion MRI. ISMRM Iberian Chapter Talk. 15 December 2023.